This is
inflammatory disease that is genetically programmed. The primarily affected
organ is the skin. This disease begins as small scaling papule. Then this
papule multiplies and form scaling plaques. These plaques tend to occur in the
scalp, elbows and knees.
This
plaques can be itchy, and when the scale is peeled away small bleeding points
appears. Often psoriasis occurs in areas of trauma. This condition often waxes
and wanes spontaneously.
Many patients
with psoriasis have abnormal nails, which are yellow and crumbly.
Destructive
arthritis is often associated with psoriasis.
There is
genetic basis for psoriasis. This hereditary predisposition is necessary before
the disease can be triggered by environmental factors. T-cells (white blood
cells) mediate the development of the psoriatic plaques.
The
environmental factors that are risk factors (can lead to psoriasis) are:
- - Alcohol
in excess
- - Streptococcal
sore throat
- -Certain
drugs
- -Trauma
to the skin
Because
this is mainly skin disease the treatment is topical. Foams, gels,
creams, shampoos and ointments that are applied directly to the skin.
Also the treatment includes topical steroids, tar preparations and calcium
modulating drugs.
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